My experiences being genetically at-risk for Parkinson’s disease linked to LRRK2 G2019S

My name is Jessi Keavney. My father, uncle, grandfather, and grandmother lived with parkinsonism and dementia, and I was a caregiver for both my dad and uncle in the final years of their lives. After I learned I carried the pathogenic LRRK2 G2019S genetic variant in 2013, I have spent more than a decade participating in over forty biomarker and observational studies focused on early detection and disease prevention. I’m a leading advocate in prodromal Parkinson’s research, contributing as a conference speaker, research and grant consultant, and co-author on multiple peer-reviewed scientific publications. I was appointed in 2026 to the federal Advisory Council on Parkinson’s Research, Care, and Services established under the National Plan to End Parkinson’s Act to help guide a unified US strategy to accelerate research, enhance care, improve diagnostics, and ultimately cure and prevent disease. I’m a mom to three sons and I work full-time as a Fractional CFO.

I created this website to consolidate links to my story, my publications, media posts, general resources for the community, relevant upcoming events, and links to get involved in LRRK2-related clinical research. Finally, I hope to connect with others like me and to engage with researchers and clinicians that work hard everyday to create a tomorrow without Parkinson’s.